The death domain kinase RIP1 links the immunoregulatory CD40 receptor to apoptoticsignaling in carcinomasPauline G. Knox,1,2 Clare C. Davies, 3Marina Ioannou,2 and Aristides G. Eliopoulos1,2 Normally, when a cell senses it’s becoming cancerous, it can press the self-destruct button to protect the body. However, mutations in this mechanism can keep a cancer cell alive. CellsContinue reading “How Does a Cancer Cell Hit The Big Red Button?”
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Scientists Arm Immune Cells To Combat Aggressive Brain Tumors: Early Trial Results
Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial Christine E. Brown, Jonathan C. Hibbard, Darya Alizadeh, M. Suzette Blanchard, Heini M. Natri, Dongrui Wang, Julie R. Ostberg, Brenda Aguilar, Jamie R. Wagner, Jinny A. Paul, Renate Starr, Robyn A. Wong, Wuyang Chen, Noah Shulkin, Maryam Aftabizadeh, Aleksandr Filippov, AmmarContinue reading “Scientists Arm Immune Cells To Combat Aggressive Brain Tumors: Early Trial Results”
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